This study seeks to identify the effects that low-level, in-utero and adult exposure to mercury have on the functioning of the immune system, with a particular emphasis on changes in the immune system that could lead to autoimmunity and autoimmune disease. These changes also could affect the response to infections and vaccines.
From the discoveries made in the laboratories at Weill Medical College to bedsides at two major cancer centers in New York, a long path has been traveled that is now leading to new cancer treatments. Cornell University, in partnership with the Ludwig Institute for Cancer Research, has produced and delivered a potential cancer ‘vaccine’ which has just entered clinical trials at Roswell Park Cancer Center and New York University.
Suboptimal reproductive performance of broiler breeder hens is one of the most significant problems in the poultry industry and is alleviated, in part, by managing the feed intake of these hens. Poor ovarian follicular development with disorganized hierarchies often results in simultaneous, multiple ovulations in broiler breeder hens. This tendency reduces productivity, because erratic patterns of lay occur, and eggs often have poor shell quality, which reduces the number that can be set.
Our research uses the soil worm C. elegans as a model to study genes that affect aging. Many genes that affect aging in C. elegans also work in humans. Our research will have impact on human aging and age-related diseases, such as cancer, heart disease, diabetes, and neurodegeneration.
The former Malaysian Breast Cancer Education Project has grown and developed since its inception in 2003. This project, which is a collaborative project between Cornell University and Universiti Putra Malaysia, has changed its title to the Cancer Education Resource and Support Center, which better expresses its expanded focus and objective.
Research in my lab is focused on the evolutionary genetics of insect-pathogen interactions. We use population genetic, quantitative genetic and genomic approaches to study how insects defend themselves against infection. We are particularly interested in understanding the genetic and environmental reasons why individuals vary in their susceptibility to infection, how interactions with pathogens shape the evolution of host immunity, and how immune defense is intertwined with other components of host physiology.
Identify genes associated with seed development, germination, vigor, and dormancy
The project aims to inventory and describe the global diversity of catfishes. Catfishes are an extremely diverse, ecologically significant, and commercially important group of fishes.
Expression of insect desaturase transgenes in yeast cells and plants represents a technological innovation with potential impacts in "green chemistry," i.e., for the production of unsaturated fatty acid precursors of insect pheromones, and in developing insect- and pathogen-resistant crop plants.
We are investigating the communication function of different learning strategies in birds. We are studying the banded wren, a moderately age-restricted learner, and the mockingbird, an open-ended learner. This project focuses on the signal function and delivery patterns of different learned song types during male-male countersinging interactions and courtship/mate attraction.