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CALS Research and Impact

Information about CALS research projects and their impact throughout the world

CALS projectJanuary 2008 - December 2009

Production of movements by the brain and spinal cord

summary 
We are attempting to understand how the brain and spinal cord produce movements.
issue 
Neurological diseases as well as spinal cord injury affect the ability of people to move properly. We need to understand how normal movements are produced by the brain and spinal cord so that we can restore function after injury or disease.
response 
We have been studying the wiring of circuits in the spinal cord and have identified classes of nerve cells that are critical for producing properly coordinated movements. We did this by using an animal model (zebrafish) in which we can image the structure and function of nerve cells in the intact animal.
impact 
By understanding how normal movements are produced, we can better develop strategies to repair the nervous system after damage, such as after spinal injury or as a consequence of diseases that affect movements.
funding type 
Unspecified
federal funding 
National Institutes of Health
researchers involved 
  • Fetcho, Joseph
organizations involved 
Institute for Physiological Sciences
University of Chicago
academic priority area 
New Life Sciences
contribution area 
Research
domestic geographic focus 
New York
Tompkins
USDA topic area 
Improve Nutrition and Health
timeframe 
January 2008 - December 2009